A declare that ingesting tea may shield folks towards creating kind 2 diabetes has been met with warning from a number of specialists forward of the annual assembly of the European Association for the Study of Diabetes.
The declare is that individuals who drink 4 or extra cups of tea day by day – particularly inexperienced, Oolong, or black tea – are 17% much less more likely to develop kind 2 diabetes than those that don’t drink tea. Drinking fewer cups of tea per day was not discovered to confer any profit.
“Our results are exciting because they suggest that people can do something as simple as drinking four cups of tea a day to potentially lessen their risk of developing type 2 diabetes,” Xiaying Li of Wuhan (China) University of Science and Technology is quoted as saying in an official EASD press launch.
“It is possible that particular components in tea, such as polyphenols, may reduce blood glucose levels, but a sufficient amount of these bioactive compounds may be needed to be effective,” Dr. Li added.
“The words ‘suggest’ and ‘potentially’ are crucial here,” stated Kevin McConway, PhD, MSc, MBA, emeritus professor of utilized statistics at The Open University, stated in a separate assertion to the press that reeled in Dr. Li’s enthusiasm.
“Tea drinking would only be useful for reducing diabetes risk if the tea drinking causes reductions in risk, that is, if the risk is reduced if you drink the tea and not if you don’t – and this study simply can’t show whether it does this or not,” Dr. Conway pressured.
Naveed Sattar, FMedSci FRCPath FRCPGlas FRSE, professor of metabolic medication on the University of Glasgow, was additionally cautiously important. “There is no good trial evidence whatsoever that the chemicals in tea prevent diabetes,” he noticed individually.
“So, I suspect its more about tea being healthier (less calorific) than many alternative drinks or tea drinkers leading healthier lives more generally.”
Dr. Sattar added that it may very well be that individuals who drink tea may also be avoiding ingesting extra dangerous sugary drinks and produce other well being behaviors which may cause them to have a decrease danger for kind 2 diabetes.
Time for Tea?
Dr. Li will current the findings of two analyses on Sept. 21 on the EASD assembly: the primary a big observational cohort research and the second an up to date systematic overview and meta-analysis.
For the cohort research, Dr. Li and her coauthors took information on greater than 5,100 adults who had participated within the long-running and ongoing China Health and Nutrition Survey (CHNS). Information on tea ingesting conduct was extracted from questionnaires that had been crammed out at two time factors – 1997 and 2009 – they usually decided whether or not folks had developed kind 2 diabetes in keeping with American Diabetes Association standards.
Nearly half, 45.8%, had been discovered to be tea drinkers, and 10% of the inhabitants they sampled had developed kind 2 diabetes. No affiliation between tea ingesting and sort 2 diabetes growth was discovered, nonetheless, with the hazard ratio evaluating tea drinkers and non–tea drinkers sitting firmly at 1.02. Moreover, a sensitivity evaluation that excluded contributors who had developed kind 2 diabetes within the first 3 years of follow-up didn’t change the consequence.
Things had been barely completely different when Dr. Li and associates carried out their meta-analysis that concerned analyzing information on greater than 1 million contributors in 19 research carried out in eight international locations that had been printed as much as September 2021.
Here, they discovered there was a major (P < .003) linear affiliation between tea consumption and having kind 2 diabetes, with the relative danger of creating kind 2 diabetes reducing by 0.986 for each extra cup of tea that was drunk.
HRs for the event of kind 2 diabetes in tea drinkers versus non–tea drinkers had been 1.00 for many who drank lower than one cup per day, 0.96 for many who had one to 2 cups, and 0.84 for many who drank 4 or extra cups.
“While more research needs to be done to determine the exact dosage and mechanisms behind these observations, our findings suggest that drinking tea is beneficial in reducing the risk of type 2 diabetes, but only at high doses (at least 4 cups a day)”, stated Dr. Li.
Perhaps, “we did not find an association between tea drinking and type 2 diabetes in our cohort study because we did not look at higher tea consumption,” she added.
Tempest in a Teacup
“This is large, observational data. It’s not a randomized controlled trial so there’s plenty of room for data to be misunderstood,” warned Matt Sydes, MSc, professor of medical trials & methodology on the MRC Clinical Trials Unit, University College London.
(*2*) added Dr. Sydes.
“Being only a conference abstract, it is difficult to assess the quality of this research,” Baptiste Leurent, PhD, a medical statistician additionally working at University College London, stated. Not solely was the cohort research observational, so had been all the opposite research included within the meta-analysis, he identified.
“Therefore, no cause-effect conclusions can be drawn. The association could simply be due to other factors, such as those drinking more tea having a healthier lifestyle. It does not seem that the authors tried to control for confounders, which is usually difficult in meta-analysis,” Dr. Leurent stated.
“There is reason to be a bit skeptical at this point; we really need to have the full details to assess it properly,” stated Jonathan Cook of the Centre for Statistics in Medicine on the University of Oxford (England). “It’s a fair attempt to look at this, but not cutting edge, [using] fairly standard approaches.”
Similar research have proven a diminished danger related to espresso ingesting, famous Duane Mellor, PhD, a registered dietitian and senior instructing fellow at Aston University in Birmingham.
“The important take-home message is that lifestyle is important in managing risk of developing type 2 diabetes,” Dr. Mellor stated.
“That includes choosing low-calorie drinks including mainly water as well as unsweetened tea and coffee as your drinks of choice as part of a healthy lifestyle.”
The research was funded by the Young Talents Project of Hubei Provincial Health Commission, the Science and Technology Research Key Project of Education Department of Hubei Province, the Sanuo Diabetes Charity Foundation, and the Xiangyang Science and Technology Plan Project, all based mostly in China. Dr. Li had no conflicts of curiosity to reveal. Dr. McConway is a Trustee and on the advisory committee of The Science Media Centre. Dr. Sattar has consulted for a lot of corporations that make diabetes and cardiovascular medicine and has been concerned in a number of trials of life-style approaches for the prevention and remission of diabetes. Dr. Sydes, Dr. Leurent, Dr. Cook, and Dr. Mellor had no conflicts of curiosity to report.
This story initially appeared on MDedge.com, a part of the Medscape Professional Network.